Journal Club

2021.04.21
Seowon Choi

Ghofran Othorm et el.

Pan-cancer proteomgenomic analysis reveals long and circular noncoding RNAs encoding peptides

2021.04.14
Minhak Choi

Jonathan R. Belyeu et al.

De novo structural mutation rates and gamete-of-origin biases revealed through genome sequencing of 2,396 families

2021.04.07
Seokju Park

Robert Buschauer et al.

The Ccr4-Not complex monitors the translating ribosome for codon optimality

2021.03.31
Kyungtae Lee

Jinyang Zhang et al.

Comprehensive profiling of circular RNAs with nanopore sequencing and CIRI-long

2021.03.24
Dohun Yi

E. Agirre et al.

Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition

2021.02.24
Vipin Menon

Kim Hui Kwon et al.

Predicting the efficiency of prime editing guide RNAs in human cells

2021.02.17
Sangho Yoon

Yuan Zhou et.al.

Single-Cell Multiomics Sequencing Reveals Prevalent Genomic Alterations in Tumor Stromal Cells of Human Colorectal Cancer

2021.01.29
Hanji Kim

Nan Miles Xi et.al

Benchmarking Computational Doublet-Detection Methods for Single-Cell RNA Sequencing Data,

2021.01.21
Youxi Cui

Hudson WH et.al

Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells

2021.01.14
Eungyeong Park

Chen S et.al.

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

2021.01.14
Sungjin Pyo

Viorel simion et.al

A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

2021.01.05
Minhak Choi

Kiran V. Garimella et.al.

Detection of simple and complex de novo mutations with multiple reference sequences

2021.01.03
Seowon Choi

Liang W.C. et.al

Translation of the circular RNA circb-catenin promotes liver cancer cell growth through activation of the Wnt pathway

2020.12.21
Seokju Park

Charlie et al

The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation

2020.12.15
Dohun Yi

Isac Lee et.al.

Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

2020.12.04
Kyungtae Lee

Kevin Lehrigrand et al

High throughput error corrected Nanopore single cell transcriptome sequencing

2020.11.7
Vipin Menon

Andrew V Anzalone et al

Search and replace genome editing without double strand breaks or donor DNA

2020.11.25
Youxi Cui

Per Johnsson et.al

Transcriptional kinetics and molecular functions of long non-coding RNAs

2020.11.18
Hanji Kim

Abha S Bais et al

scds : computational annotation of doublets in single-cell RNA sequencing data

2020.10.27
Eungyeong Park

Junbin Qian et al

A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling

2020.10.26
Sungjin Pyo

Thomas Krausgruber et al

Structural cells are key regulators of organ-specific immune responses

2020.10.14
Minhak Choi

Justin M Zook et al

A robust benchmark for dectection of germline large deletions and insertions

2020.09.17
Seowon Choi

Timoteo GD

Modulation of circRNA Metabolism by m 6 A Modification

2020.09.12
Seokju Park

Wang, Jingjing, et al

XPO5 promotes primary miRNA processing independently of RanGTP

2020.09.03
Dohun Yi

Zaccara S et.al.

A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA

2020.08.27
Kyungtae Lee

Chun-Jie Guo et al

Distinct Processing of lncRNAs Contributes to Nonconserved Functions in Stem Cells

2020.08.26
Vipin Menon

Nahye kim et al

Prediction of the sequence-specific cleavage activity of Cas9 variants

2020.08.17
Sangho Yoon

Lei Zhang et al.

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

2020.08.12
Hanji Kim

Jean-Charles Boisset et al

Mapping the physical network of cellular interactions

2020.08.05
Youxi Cui

Haitao Luo et al

Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity

2020.07.29
Sungjin Pyo

Yongsheng Li et al.

Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers

2020.07.15
Eungyeong Park

Benjamin Izar et al

A single-cell landscape of high-grade serous ovarian cancer

2020.07.01
Seowon Choi

Marina Reixachs-Solé et al

Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome

2020.06.24
Minhak Choi

Shan Jiang et al

Identification of de novo mutations in prenatal neurodevelopment-associated genes in schizophrenia in two Han Chinese patient-sibling family-based cohorts

2020.06.24
Kyungtae Lee

Yan Song et al

Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation

2020.06.17
Dohun Yi

William Stephenson et al

Direct detection of RNA modifications and structure using single molecule nanopore sequencing

2020.06.17
Seokju Park

Johannes Linder et al

Deep exploration networks for rapid engineering of functional DNA sequences

2020.06.10
Sangho Yoon

Hae-Ock Lee et al

Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

2020.06.10
Vipin Menon

Hui Kwon Kim et al

High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

2020.06.03
Hanji Kim

Daniel A Skelly et al

Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart

2020.06.03
Youxi Cui

Kevin C H et al

QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data

2020.05.6
Seokju Park

Asako McCloskey et al

hnRNP C Tetramer Measures RNA Length to Classify RNA Polymerase II Transcripts for Export

2020.05.6
Dohun Yi

Yi Tay

SYNTHESIZER: Rethinking Self-Attention in Transformer Models

2020.05.27
Sungjin Pyo

Zhilei Bian et al

Deciphering human macrophage development at single-cell resolution

2020.05.27
Eungyeong Park

Nayoung Kim etl al

Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma

2020.05.20
Hyunwoo Kim

Bjorem Gaertner

A functional screen of translated pancreatic lncRNAs identifies a microprotein-independent role for LINC00261 in endocrine cell differentiation

2020.05.20
Seowon Choi

Peng Zhang

Comprehensive identification of alternative back-splicing in human tissue transcriptomes

2020.05.13
Minhak Choi

Yu Liang et al

Comparative Analysis for the Performance of Variant Calling Pipelines on Detecting the de novo Mutations in Humans

2020.04.29
Kyungtae Lee

Tetsurato Hayashi

Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs

2020.04.29
Vipin Menon

Russel T Walton et al

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

2020.04.22
Sangho Yoon

Elisabeta Mereu et al

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects

2020.04.22
Hanji Kim

Christopher S McGinnis et al

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

2020.04.15
Youxi Cui

Runsheng Li et al

Direct full-length RNA sequencing reveals unexpected transcriptome complexity during Caenorhabditis elegans developmen

2020.04.15
Eungyeong Park

Tabula Consortium

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

2020.04.08
Hyunwoo Kim

Jin Chen et al

Pervasive functional translation of non canonical human open reading frames

2020.04.08
Sungjin Pyo

Yongsheng Li et al.

Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers

2020.02.26
Minhak Choi

Consortium

Pan-cancer analysis of whole genomes The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium

2020.02.26
Seowon Choi

Jinyang Zhang et al

Accurate quantification of circular RNAs identifies extensive circular isoform switching events

2020.02.19
Seokju Park

Brian Reichholf et al

Time-Resolved Small RNA Sequencing Unravels the Molecular Principles of MicroRNA Homeostasis

2020.02.19
Jang-il sohn

Yilong Li et al

Patterns of somatic structural variation in human cancer genomes

2020.02.12
Dohun Yi

Alexa BR Mcintyre et al

Limits in the detection of m6A changes using MeRIP/m6A-seq

2020.02.05
Vipin Menon

Hui Kwon Kim et al

High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

2020.02.05
Sangho Yoon

LichunMa, et al.,

Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

2020.01.29
Youxi Cui

Leiming You, et al

APASdb: a database describing alternative poly(A) sites and selection of heterogeneous cleavage sites downstream of poly(A) signals

2020.01.29
Eungyeong Park

Diether Lambrechts et al

Phenotype molding of stromal cells in the lung tumor microenvironment

2020.01.22
Seowon Choi

Joana Carlevaro et al

Global Positioning System: Understanding Long Noncoding RNAs through Subcellular Localization

2020.01.22
Hyunwoo Kim

Thomas F. Martinez et al

Accurate annotation of human protein-coding small open reading frames

2020.01.08
Minhak Choi

Kijong Yi et al

Patterns and mechanisms of structural variations in human cancer

2020.01.08
Sungjin Pyo

Barbara Maria eta la

Neutrophils escort circulating tumour cells to enable cell cycle progression

Seminars

© 2014 by BIG Lab. All copyrights reserved. Editor: JWNAM

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