gRNA Designer

Vipin Menon, Jangil Sohn, and Jin-Wu Nam, CGD: Comprehensive Guide Designer for CRISPR-Cas Systems, Computational and Structural Biotechnology Journal, 18:814-820, 2020.

Mass-cytometry & scRNAs-eq - Nanoparticle Toxicity

My Kieu Ha, Sook Jin Kwon, Jang‐Sik Choi, Nguyen Thanh Nguyen, Jaewoo Song, Yangsoon Lee, Young‐Eun Kim, Incheol Shin, Jin‐Wu NamTae Hyun Yoon. Mass Cytometry and Single‐Cell RNA‐seq Profiling of the Heterogeneity in Human Peripheral Blood Mononuclear Cells Interacting with Silver Nanoparticles, Small, 2020,

Single cell analysis of fly lymph gland

Bumsik Cho*, Sang-Ho Yoon*, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Seok Joon Moon, Norbert Perrimon, Jin-Wu Nam#, Jiwon Shim#, Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila, bioRxiv, doi:, 2020.

* These authors are contributed equally    # Co-correspondence

Single cell analysis of fly bloods

Sudhir Gopal Tattikota, Yanhui Hu, Yifang Liu, Bumsik Cho, Victor Barrera, Michael Steinbaugh, Sang-Ho Yoon, Aram Comjean, Fangge Li, Franz Dervis, Ruei-Jiun Hung, Jin-Wu Nam, Shannan Ho Sui, Jiwon Shim, Norbert Perrimon, A single-cell survey of Drosophila blood, eLife. 2020; 9: e54818.

HERES-Wnt signaling regulator

Bo-Hyun You*, Jung-Ho Yoon*, Hoin Kang, Eun Kyung Lee, Sang Kil Lee#, and Jin-Wu Nam#, HERES, a lncRNA that Regulates Canonical and Noncanonical Wnt Signaling Pathways via Interaction with EZH2, PNAS, 116 (49) 24620-24629, 2019  

* These authors are contributed equally    # Co-correspondence

Genome and Transcriptome Analyses of Jejuma

Krishnamoorthy Srikanth, Nam-Young Kim, WonCheoul Park, Jae-Min Kim, Kwon-Do Kim, Kyung-Tai Lee , Ju-Hwan Son, Han-Ha Chai, Jung-Woo Choi, Gul-Won Jang, Heebal Kim, Youn-Chul Ryu, Jin-Wu Nam, Jong-Eun Park, Jun-Mo Kim & Dajeong Lim. Comprehensive genome and transcriptome analyses reveal genetic relationship, selection signature, and transcriptome landscape of small-sized Korean native Jeju horse. Scientific Reports, 9:16672, 2019.

Assessment of Inflammation in Pulmonary Artey Hypertension

Jun-Bean Park, ..., Jae-Hoon Choi, Jin-Wu Nam,Hyung-Kwan Kim, Yun-Sang Lee, Jae Min Jeong, Yong-Jin Kim, Jin Chul Paeng, and Seung-Pyo Lee. ​Assessment of inflammation in pulmonary artery hypertension by 68Ga-Mannosylated Human serum albumin. American Journal of Respiratory and Critical Care Medicine, 2019 Jul 19. doi: 10.1164/rccm.201903-0639O.

UPF1-mediated miRNA targeting

Jeongyoon Park*, Jwa-Won Seo*, Narae Ahn, Seokju Park, Jungwook Hwang#, and Jin-Wu Nam#. UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation, Nature Communications, 10:4181, 2019.

* These authors are contributed equally    # Co-correspondence

Functional Elements of Human XIST

Hyeon Lee*,  Ramu Gopalappa*, Hongjae Sunwoo*, Seowon Choi, Suresh Ramakrishna, Jeannie Lee,  Hyongbum (Henry) Kim#,  Jin-Wu Nam#En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements, Nucleic Acids Res., 47:8, 3875–3887, 2019.

* These authors are contributed equally    # Co-correspondence

ARE-mediated mRNA decay

Incheol Ryu, Yeonkyoung Park, Jwa-Won Seo, Ok Hyun Park, Hongseok Ha, Jin-Wu Nam and Yoon Ki Kim. HuR stabilizes a polyadenylated form of replication-dependent histone mRNAs under stress conditions. FASEB J. 33(2):2680-269, 2019.

The small peptide in lncRNAs

Seo-Won Choi*, Hyunwoo Kim*, and Jin-Wu Nam, The small peptide world in long non-coding RNAs, Briefings in Bioinformatics, 20(5): 1853–1864, 2019.

* These authors contributed equally

Transcriptome Analysis of Non-Foamy cells in Atherosclerotic Murine Models

Kyeongdae Kim , Dahee Shim , Jun Seong Lee , Konstantin Zaitsev , Jesse W Williams , Ki-Wook Kim , Man-Young Jang , Hyung Seok Jang , Tae Jin Yun , Seung Hyun Lee , Won Kee Yoon , Annik Prat , Nabil G Seidah , Jungsoon Choi , Seung-Pyo Lee , Sang-Ho Yoon , Jin Wu Nam , Je Kyung Seong , Goo Taeg Oh , Gwendalyn Randolph , Maxim N Artyomov , Cheolho Cheong , and Jae-Hoon Choi, Transcriptome Analysis Reveals Non-Foamy Rather than Foamy Plaque Macrophages Are Pro-Inflammatory in Atherosclerotic Murine Models, Circulation Res. 2018.

HSF2 and lncRNAs in black tissues

Hyosun Hong*, Han-Ha Chai*, Kyoungwoo Nam, Dajeong Lim, Kyung-Tai Lee, Yoon Jung Do, Chang-Yeon Cho and Jin-Wu Nam, HSF2 Co-regulates Protein-coding and Long Non-coding RNA Genes Specific to Black Tissues of the Black Chicken, Yeonsan Ogye, International Journal of Molecular Sciences, 19(8), 2359. 2018.

* These authors contributed equally  

Ogye draft genome and transcriptomes

Jang-il Sohn*, Kyoungwoo Nam*, Hyosun Hong*, Jun-Mo Kim*,  Dajeong Lim, Kyung-Tai Lee, Yoon Jung Do, Chang Yeon Cho, Namshin Kim, Han-Ha Chai# and Jin-Wu Nam# Whole genome and transcriptome maps of the entirely black native Korean chicken breed Yeonsan Ogye, GigaSciences, giy086,, 2018,

* These authors contributed equally  # Co-correspondence


Jung-Ho Yoon, Bo-Hyun You, Chan Hyuk Park, Yeong Jin Kim, Jin-Wu Nam, and Sang Kil Lee. The long noncoding RNA LUCAT1 promotes tumorigenesis by controlling ubiquitination and stability of DNA methyltransferase 1 in esophageal squamous cell carcinoma. Cancer Letters417:47-57, 28 March 2018.

lncRNA annotation

Seo-Won Choi and Jin-Wu Nam, TERIUS: accurate prediction of lncRNA via high-throughput sequencing data representing RNA binding protein association. BMC Bioinformatics, 19(Suppl 1):41, 2018.

De Novo Whole Genome Assembly

Jang-il Sohn and Jin-Wu Nam, The Present and Future of De Novo Whole Genome Assembly, Briefings in Bioinformatics, 19(1):23-40. 2018.

DROSHA self-regulation

Dooyoung Lee, Jin-Wu Nam, and Chanseok Shin, DROSHA targets its own transcript to modulate alternative splicing. RNA, Jul;23(7):1035-1047, 2017.

Targeted Exomse Sequencing in TN-Breast Cancer

Hae Min Jeong, Ryong Nam Kim, Mi Jeong Kwon, Ensel Oh, Jinil Han, Se Kyung Lee, Jong-Sun Choi, Sara Park, Seok Jin Nam, Gyung Yup Gong, Jin Wu Nam, Doo Ho Choi, Hannah Lee, Byung-Ho Nam, Yoon-La Choi and Young Kee Shin. Targeted exome sequencing of Korean triple-negative breast cancer reveals homozygous deletions associated with poor prognosis of adjuvant chemotherapy-treated patients. Oncotarget, 8:61538-61550, 2017.

Co-assembly of Transcriptome

Bo-Hyun You, Sang-Ho Yoon, and Jin-Wu Nam. High-Confidence Coding and Noncoding Transcriptome Maps. Genome Res. 27(6):1050-1062, 2017.

miRNA-mediated silencing of mRNA-like lncRNAs

Kyung-Tae Lee and Jin-Wu Nam. Post-transcriptional and translational regulation of mRNA-like long non-coding RNAs by microRNAs in early developmental stages of zebrafish embryos. BMB Rep. 2017 Mar 21. pii: 3769.

Endogenous Cpf1 efficiency predictor

Hui Kwon Kim, Myungjae Song, Jinu Lee, Adrussery. Vipin Menon, Soobin Jung, Young-Mook Kang, Euijeon Woo, Jin-Wu Nam, and Hyongbum (Henry) Kim. In vivo high-throughput profiling of CRISPR-Cpf1 activity based on target sequence composition. Nature Methods. 14:153–159, 2017.

Network-based Tumour Purity

Youngjune Park, Sangsoo Lim, Jin-Wu Nam, and Sun Kim. Measuring intratumor heterogeneity by network entropy using RNA-seq data. Sci. Rep. 6, 37767; doi: 10.1038/srep37767, 2016.

Parkinson’s disease therapy by NSCs expanded with LIN28A

Yong-Hee Rhee, Tae-Ho Kim, A-Young Jo, Mi-Yoon Chang, Chang-Hwan Park,Sang-Mi Kim, Jae-Jin Song, Sang-Min Oh, Sang-Hoon Yi, Hyeon Ho Kim, Bo-Hyun You, Jin-Wu Nam, and Sang-Hun Lee​, LIN28A enhances the therapeutic potential of cultured neural stem cells in a Parkinson’s disease model.  Brain, 139(Pt 10):2722-2739, 2016.

Bifunctional RNAs-Review

Jin-Wu Nam, Seo-Won Choi, and Bo-Hyun You, Incredible RNA: Dual Functions of Coding and Noncoding. Mol. Cells. 39(5):367-374. 2016.


Pseudo-Reference-Based Assembly of Vertebrate Transcriptomes

Kyoungwoo Nam*, Heesu Jeong*, Jin-Wu Nam, Pseudo-Reference-Based Assembly of Vertebrate Transcriptomes, Genes, 7(3) : 10, 2016

* These authors contributed equally 

microRNAs in stem cell differentiation

Jiwon Shim, Jin-Wu Nam, The expression and functional roles of microRNAs in stem cell differentiation, BMB Reports, 49(1) : 3-10. 2016


micoRNA-362-3p/329 as tumor suppressor

Hoin Kang, Chongtae Kim, Heejin Lee, Jun Gi Rho, Jwa-Won Seo, Jin-Wu Nam, Woo Keun Song, Suk Woo Nam, Wook Kim and Eun Kyung Lee, Downregulation of microRNA-362-3p and microRNA-329 promotes tumor progression in human breast cancer. Cell Death & Diff., 23(3):484-95. 2016.


MinHyeok Kim, Bo-Hyun You, and Jin Wu Nam. Global Estimation of the 3' Untranslated Region Landscape Using RNA Sequencing. Methods, 83:111-117. 2015.

TargetScan 7.0

Vikram Agarwal, George W. Bell, Jin-Wu Nam, David P.Bartel, Predicting effective microRNA target sites in mammalian mRNAs. eLife, 4:e05005, 2015.

Cell-type specific miRNA targeting

J.-W. Nam, O. Rissland, D. Kopstein, V. Agarwal, C. Jan, M. Yildrim and D. Bartel, Global analyses of the effect of different cellular contexts on microRNA targeting. , Mol Cell, 53(6), 1031–1043, 2014.

miRNA-mediated cleavage target

June Hyun Park, Soungyub Ahn, Soyoung Kim, Junho Lee, Jin-Wu Nam*, Chanseok Shin* Degradome sequencing reveals an endogenous microRNA target in C. elegans, FEBS Letters 587(2013) 964-969, 2013.

lncRNAs in C. elegans

J.-W. Nam and D. Bartel, Long non-coding RNAs in C.elegans. Genome Research. 22: 2529-2540, 2012. Media: Nature Method.

Centered sites of miRNAs

C.Shin*, J.-W. Nam*, K.Farh*, R.Chiang, A.Shkumatava, and D.Bartel. Expanding the MicroRNA Targeting Code: A Novel Type of Site with Centered Pairing., Mol Cell, 38(6):789-802, 2010. Highlight paper

The common miR-8/miR-200 targeting

S. Hyun*, J.H. Lee*, H. J*. J.-W. Nam, B.J. Namkoong, G. Lee, J. Chung, V.N. Kim, Conserved MicroRNA miR-8/miR-200 and Its Target USH/FOG2 Control Growth by Regulating PI3K, Cell, 139(6):1096-1108, 2009.

Book chapter

B.-T Zhang and J.-W. Nam Supervised learning approach for microRNA studies, Machine Learning in Bioinformatics, Chapter 16, John Wiley & Sons, 2008.

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miR-29 and cancer

S. Y. Park*, J. H. Lee*, M. Ha, J.-W. Nam and V. N. Kim. "miR-29 miRNAs activate p53 by targeting p85a and CDC42" Nature Structural and Molecular Biology 16(1):23-9, 2009


J.H. Namkung, J.-W. Nam, and TS Park. Identification of eQTL by the interaction analysis using genetic algorithm. BMC proc. (Suppl 1): S69, 2007.

The tertiary structure of pre-miRNA

J.-W. Nam, I.-H. Lee, K.-B. Hwang, S.-B. Park, and B.-T. Zhang, Dinucleotide step parameterization of pre-miRNAs using multi-objective evolutionary algorithms. EvoBio, 2007.

Plant miRNAs

M. Oh, H. Lee, Y.-K. Kim, J.-W. Nam, J.-K. Rhee, B.-T. Zhang, V.N. Kim, I. Lee, Identification and characterization of small RNAs from vernalized Arabidopsis thaliana, Journal of Plant Biology, 50(5):562-572, 2007